Publikacje

Telomerase and drug resistance in cancer.
Lipińska N., Romaniuk A., Paszel-Jaworska A., Toton E., Kopczynski P., Rubis B.
Cell Mol Life Sci. 2017 Jun 16. doi: 10.1007/s00018-017-2573-2.

hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer.
Barczak W., Suchorska W., Sobecka A., Bednarowicz K., Machczyński P., Golusiński P., Rubiś B., Masternak M.M., Golusiński W.
Mol. Med. Rep. 2017: Vol. 16, nr 1, s. 441-446.

Nanoscale size effect in in situ titanium based composites with cell viability and cytocompatibility studies.
Miklaszewski A., Jurczyk M.U., Kaczmarek M., Paszel-Jaworska A., Romaniuk A., Lipińska N., Żurawski J., Urbaniak P., Jurczyk M.
Mater. Sci. Eng. C Mater. Biol. Appl. 2017: Vol. 73, s. 525-536.

Semisynthetic oleanane triterpenoids inhibit migration and invasion of human breast cancer cells through downregulated expression of the ITGB1/PTK2/PXN pathway.
Lisiak N., Paszel-Jaworska A., Totoń E., Rubiś B., Pakuła M., Bednarczyk-Cwynar B., Zaprutko L., Rybczyńska M.
Chem. Biol. Interact. 2017: Vol. 268, s. 136-147.

Strain-dependent mutational effects for Pepino mosaic virus in a natural host.
Minicka J., Elena S.F., Borodynko-Filas N., Rubiś B., Hasiów-Jaroszewska B.
BMC Evol. Biol. 2017: Vol. 17, nr 1, art. 67, s. 1-11.

Effect of growth differentiation factor-9 C447T and G546A polymorphisms on the outcomes of in vitro fertilization.
Serdyńska-Szuster M., Jędrzejczak P., Ożegowska K.E., Hołysz H., Pawelczyk L., Jagodziński P.P.
Mol. Med. Rep. 2016: Vol. 13, nr 5, s. 4437-4442.

Formaldehyde is a potent proteotoxic stressor causing rapid heat shock transcription factor 1 activation and Lys48-linked polyubiquitination of proteins.
Ortega-Atienza S., Rubiś B., McCarthy C., Zhitkovich A.
Am. J. Pathol. 2016: Vol. 186, nr 11, s. 2857-2868.

In vitro biocompatibility of anodized titanium with deposited silver nanodendrites.
Kaczmarek M., Jurczyk K., Koper J.K., Paszel-Jaworska A., Romaniuk A., Lipińska N., Żurawski J., Urbaniak P., Jakubowicz J., Jurczyk M.U.
J. Mater. Sci. 2016: Vol. 51, nr 11, s. 5259-5270.

In vitro biocompatibility of titanium after plasma surface alloying with boron
Kaczmarek M., Jurczyk M.U., Miklaszewski A., Paszel-Jaworska A., Romaniuk A., Lipińska N., Żurawski J., Urbaniak P., Jurczyk K.
Mater. Sci. Eng. C Mater. Biol. Appl. 2016: Vol. 69, s. 1240-1247.

Increased proapoptotic activity of electron beam irradiated doxorubicin and epirubicin in multidrug-resistant human leukemic cells.
Paszel-Jaworska A., Totoń, Dettlaff K., Kaczmarek A., Bednarski W., Oszczapowicz I., Jelińska A., Rybczyńska M.
Chem. Biol. Interact. 2016: Vol. 258, s. 69-78.

Novel promising estrogenic receptor modulators: cytotoxic and estrogenic activity of benzanilides and dithiobenzanilides.
Kucińska M., Giron M.D., Piotrowska H., Lisiak N., Granig W.H., Lopez-Jaramillo F.J., Salto R., Murias M., Erker T.
PLoS ONE 2016: Vol. 11, nr 1, e0145615, s. 1-16.

Selective anticancer activity of the novel thiobenzanilide 63T against human lung adenocarcinoma cells.
Kucińska M., Piotrowska-Kempisty H., Lisiak N., Kaczmarek M., Dams-Kozłowska H., Granig W.H., Höferl M., Jäger W., Zehl M., Murias M., Erker T.
Toxicol. In Vitro 2016: Vol. 37, s. 148-161.

Telomere length assessment in leukocytes presents potential diagnostic value in patients with breast cancer.
Barczak W., Rozwadowska N., Romaniuk A., Lipińska N., Lisiak N., Grodecka-Gazdecka S., Książek K., Rubiś B.
Oncol. Lett. 2016: Vol. 11, nr 3, s. 2305-2309.

The synthetic oleanane triterpenoid HIMOXOL induces autophagy in breast cancer cells via ERK1/2 MAPK pathway and Beclin-1 up-regulation.
Lisiak N., Totoń E., Rubiś B., Majer B., Rybczyńska M.
Anticancer Agents Med. Chem. 2016: Vol. 16, nr 8, s. 1066-1076.

Zapotin (5,6,2',6'-tetramethoxyflavone) modulates the crosstalk between autophagy and apoptosis pathways in cancer cells with overexpressed constitutively active PKC.
Totoń E., Romaniuk A., Budzianowski J., Hofmann J., Rybczyńska M.
Nutr. Cancer 2016: Vol. 68, nr 2, s. 290-304.

DAT1 methylation changes in alcohol-dependent individuals vs. controls.
Jasiewicz A., Rubiś B., Samochowiec J., Małecka I., Suchanecka A., Jabłoński M., Grzywacz A.
J. Psychiatr. Res. 2015: Vol. 64, s. 130-133.

Impact of common ABCB1 polymorphism on pharmacokinetics and pharmacodynamics of clopidogrel and its metabolites.
Karaźniewicz-Łada M., Danielak D., Rubiś B., Burchardt P., Komosa A., Lesiak M., Główka F.
J. Clin. Pharm. Ther. 2015: Vol. 40, nr 2, s. 226-231.

Proapoptotic activity and ABCC1-related multidrug resistance reduction ability of semisynthetic oleanolic acid derivatives DIOXOL and HIMOXOL in human acute promyelocytic leukemia cells.
Paszel-Jaworska A., Rubiś B., Bednarczyk-Cwynar B., Zaprutko L., Rybczyńska M.
Chem. Biol. Interact. 2015: Vol. 242, s. 1-12.

Telomere shortening in Down syndrome patients - when does it start?
Gruszeczka A., Kopczyński P., Cudziło D., Lipińska N., Romaniuk A., Barczak W., Rozwadowska N., Totoń E., Rubiś B.
DNA Cell Biol. 2015: Vol. 34, nr 6, s. 412-417.

Universal real-time PCR-based assay for lentiviral titration.
Barczak W., Suchorska W., Rubiś B., Kulcenty K.
Mol. Biotechnol. 2015: Vol. 57, nr 2, s. 195-200.

Autofagia, nowe perspektywy w terapii przeciwnowotworowej.
Lisiak N., Totoń E., Rybczyńska M.
Post. Hig. Med. Dośw. 2014: T. 68, s. 925-935.

Beclin-1 and its role as a target for anticancer therapy.
Totoń E., Lisiak N., Sawicka P., Rybczyńska M.
J. Physiol. Pharmacol. 2014: Vol. 65, nr 4, s. 459-467.

In vitro biocompatibility of Ti-45S5 bioglass nanocomposites and their scaffolds.
Kaczmarek M., Jurczyk M.U.,  Rubiś B., Banaszak A., Kolecka A., Paszel A., Jurczyk K., Murias M., Sikora J., Jurczyk M.
J. Biomed. Mater. Res. A 2014: Vol. 102A, nr 5, s. 1316-1324.

Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (MIXOMOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells.
Lisiak N., Paszel-Jaworska A., Bednarczyk-Cwynar B., Zaprutko L., Kaczmarek M., Rybczyńska M.
Chem. Biol. Interact. 2014: Vol. 208, s. 47-57.

Molecular mechanisms of biological activity of oleanolic acid - a source of inspiration for a new drugs design.
Paszel-Jaworska A., Romaniuk A., Rybczyńska M.
Mini Rev. Org. Chem. 2014: Vol. 11, nr 3, s. 330-342.

Telomerase modulation in therapeutic approach.
Romaniuk A., Kopczyński P., Książek K., Rubiś B.
Curr. Pharm. Des. 2014: Vol. 20, nr 41, s. 6438-6451.

The influence of genetic polymorphism of Cyp2c19 isoenzyme on the pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases.
Karaźniewicz-Łada M., Danielak D., Rubiś B., Burchardt P., Oszkinis G., Główka F.
J. Clin. Pharmacol. 2014: Vol. 54, nr 8, s. 874-880.